Typical dosing for Zofran (ondansetron) Adults: Chemotherapy that causes severe nausea and vomiting: A single 24 mg dose taken 30 minutes before the start of a single-day highly vomit-inducing chemotherapy. Chemotherapy that causes moderate nausea and vomiting: 8 mg dose taken 30 minutes before the start of chemotherapy, with another 8 mg dose taken 8 hours after the first dose. The dose of Zofran for hyperemesis gravidarum requiring hospitalization is a maximum of 10 milligrams via intravenous therapy (IV) every 8 hours. More typical pregnancy nausea is managed by a much. Ondansetron comes as a tablet, a rapidly disintegrating (dissolving) tablet, film, and an oral solution (liquid) to take by mouth. The first dose of ondansetron is usually taken 30 minutes before the start of chemotherapy, 1 to 2 hours before the start of radiation therapy, or 1 hour before surgery. ZOFRAN 8 mg three times daily is not a recommended regimen for the treatment of moderately emetogenic chemotherapy [see DOSAGE AND ADMINISTRATION]. Treatment response was based on the total number of emetic episodes over the 3-day trial period. See Table 8 for the details of the dosage regimens studied and results of this trial. Table 8: Emetic Episodes – Treatment Response after ZOFRAN. GlaxoSmithKline (GSK) has announced changes to the Zofran drug label to remove the 32 mg single intravenous dose. The updated label will state that ondansetron can continue to be used in adults. [09-15-2011] The U.S. Food and Drug Administration (FDA) is informing the public of an ongoing safety review of the anti-nausea drug Zofran (ondansetron, ondansetron hydrochloride and their generics). We are a rural community primary school situated in the village of Old Buckenham, Norfolk. As a primary school we have always catered for the age range 4 to 11, a seven year educational span, however in August 2018, we took on Buckenham Pre-School Group to extend our age range from 2 years old. Brand names for ondansetron include Zofran, Zofran ODT, and Zuplenz. Moderately nauseating chemotherapy: Take 8 mg tablet 30 minutes prior to chemotherapy and repeat in 8 hours, then 8 mg every 12 hours for 1 to 2 days after chemotherapy. Radiation-induced nausea and vomiting: Take 8 mg orally 1 to 2 hours prior to radiation and every 8 hours after first dose, as needed. Post-surgery. 8 mg administered 30 minutes before the start of chemotherapy, with a subsequent 8-mg dose 8 hours after the first dose. Then administer 8 mg twice a day (every 12 hours) for 1 to 2 days after completion of chemotherapy. Radiotherapy. For total body irradiation: 8 mg administered 1 to 2 hours before each fraction of radiotherapy each day. Zofran Injection (Ondansetron Hydrochloride Injection) - Multum; Zohydro ER (Hydrocodone bitartrate Extended Release Capsules) - FDA; Zohydro ER (Hydrocodone bitartrate Extended Release Capsules) - Multum; Zokinvy (Lonafarnib Capsules) - FDA; Zokinvy (Lonafarnib Capsules) - Multum; Zoladex 10.8 mg (Goserelin Acetate Implant) - FDA.